It has been noted by previous research that agents that, unlike GHRH, which interacts with the GHRH receptors, molecules that interact with the ghrelin receptors may have low specificity and support multiple streams of pituitary hormone
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309,422 However, peptide carriers and their cargos often become trapped in acidified endosomes, preventing their entry into the cytoplasm, nucleus, and other subcellular compartments
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